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With these introductory considerations in mind, I review findings from many different viruses with a particular focus on HIV and SARS-CoV-2 and consider our current understanding of the mechanisms of antibody-mediated neutralization in vitro, the antiviral mechanisms of nAbs that become relevant if effector cells are included in typical in vitro assays and the mechanisms of nAb activity against viruses in vivo

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Cellular redox balance and oxidative-stress mechanism work

Ascorbic Acid - Vitamin C for Immunity: Enhances cellular immune function and supports both innate and adaptive immunity

doi: 10.1038/nature08530 95 PompuraSLWagnerAKitzALaPercheJYosefNDominguez-VillarMet al

Cell Mol Life Sci 73:21652176