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Data were independently extracted by two reviewers into a standardized spreadsheet, and pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using a random-effects model

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Estrogens play a fundamental role in the physiology of the reproductive, cardiovascular, skeletal, and central nervous systems

In this study, we aimed to review the evidence that suggests uric acid extrarenal excretion and gut microbiome are potential risk factors for developing gout