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It has also been demonstrated that the administration of NAC can significantly improve transplant-free survival in patients affected by acute liver failure not related to acetaminophen when administered during the early stages of hepatic encephalopathy

Targeted delivery of IGF-I to spinal cord motor neurons via intramuscular injection of IGF-I, fused to non-toxic tetanus toxin fragment-C (TTC), promoted maintenance of muscle fiber innervation and prevented neuromuscular junction atrophy and fragmentation in aged muscle fibers[32]

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J Endocrinol 2004

doi:10.2169/internalmedicine.55.5956 Goyal, Hemant et al

Importantly, symptoms that pre-dated the onset of COVID-19 and did not worsen were not considered to represent LC