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Description
Likewise, SIRT3 acts as a core regulatory enzyme of mitochondrial metabolism to mediate mitophagy and suppress the accumulation of advanced glycation end-products, thereby delaying bone marrow-MSC senescence and maintaining bone homeostasis (168)

10.1007/s11101-018-9595-8

Clinical Uses Cobalamin deficiency the core indication

27,28,333 In the process of mitochondrial dysfunction, imbalanced ROS production and subsequent oxidative stress play an important role, leading to cardiac injury

Environ Pollut 290:117987

Furthermore, these findings align with the increased levels of iron and decreased autophagy observed in the brain during neurodegeneration [43]
