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utilized lentiviral vectors to modify hUC-MSCs to synthesize three critical genes involved in DA production: TH, GTP cyclohydrolase 1 (GCH1), and aromatic amino acid decarboxylase (AADC)
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NS5, the largest NS protein, exhibits two enzymatic activities: methyltransferase activity in its N-terminus and RNA-dependent RNA polymerase (RdRp) activity in its C-terminus 11,12,13

4.2 Selective high expression of one or two enzymes 4.2.1 Breast cancer PHGDH is highly expressed in approximately 70% of estrogen receptor (ER)-negative breast cancers

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Rostami R., Nourooz-Zadeh S., Mohammadi A., Khalkhali H.R., Ferns G., Nourooz-Zadeh J
The current analytical techniques often require sophisticated equipments and time-consuming sample preparation processes 25,53