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A version of this article was originally published in the Apothagram , PCCAs members-only magazine
In research settings, it is studied for its role in energy metabolism, nerve repair, and cognitive support
Preliminary results of a phase 1, first-in-human, dose escalation study of the anti-CCR8 cytolytic antibody, CHS-114 (formerly SRF114) in patients with advanced solid tumors
As a result, machine learning classification models have identified several circRNAs as potential disease biomarkers, such as circERBB2 and circCHST12 for intracerebral hemorrhage diagnosis (Bai et al., 2022), circ-0080695 for liver cancer diagnosis (Zhu et al., 2021b), circ_0059706 for acute myeloid leukemia prognosis (Ma et al., 2022b), and hsa_circ_0007919, hsa_circ_0002419, and hsa_circ_0005521 for pulmonary tuberculosis diagnosis (Yuan et al., 2022)
Widespread intronic polyadenylation inactivates tumour suppressor genes in leukemia
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