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As free CORT measurements were not feasible, levels of free plasma CORT were estimated based on plasma total cortisol, CBG and albumin concentrations with the following calculation [relative plasma total corticosterone0.85*relative plasma CBG*relative plasma total corticosterone)(0.10*relative plasma albumin*relative plasma total corticosterone)]

They express active tyrosinase and dihydroxyphenylalanine (DOPA) and are considered part of the hair follicle pigmentary unit, along with keratinocytes.6 Melanogenesis occurs within specialized lysosomes called melanosomes, which are transferred to keratinocytes via dendrites and filopodia

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doi: 10.1111/add.14234

However, in certain cases, antigens with specific chemical characteristics present in the lymph, known as free antigens, are able to directly enter the LN (61)

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