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TF neutralizes iron-induced toxicity in iRPE cells Because lipid peroxidation leads to iron overload in iRPE cells, we further investigated the mechanisms of action of TF on iRPE cells exposed to FeCl 3 associated with nitrilotriacetate, which forms a stable iron complex in solution

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doi:10.1111/imr.13278 Gonzalez AL, Dungan MM, Smart CD, Madhur MS, Doran AC

These findings highlight that early-life Mn exposure has significant neurodevelopmental implications, with the developing brain being especially sensitive to Mn accumulation

Furthermore, the alkaloid SZ-A, derived from mulberry twigs, enhances endothelial cell function and mitigates inflammatory responses by reducing CXCL-10 secretion from M1 macrophages, offering a novel therapeutic approach for atherosclerosis treatment (109)