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Description
The name Trinity-X refers to its triple-receptor mechanismthree pathways activated by one molecule

Library preparation and sequencing were performed, followed by the trimming of sequence reads using fastp v.0.23.13 to remove potential adaptor sequences and low-quality nucleotides
doi: 10.1007/s40257-018-0409-y

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Nrf2 signaling pathway is an important way to regulate cellular oxidative stress, which plays an important role in DILI (Tong et al., 2006)
However, with the prevalence of skin permeation enhancement methods (such as microneedles and laser) used in cosmetic and pharmaceutical industry 15 , copper compounds may pose a higher risk to cause skin irritation, which necessitates a thorough skin toxicity testing