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The discovery and repeated confirmation of melatonin as an oxygen-based free radical scavenger and antioxidant represents a paradigm shift (61, 7582), especially since this applied to melatonin at both the pinealocyte level, and to extrapineal cells (Source # 2)

This makes it a potential option for those who need higher doses or have trouble absorbing vitamin C through their normal diet or supplements

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Consequently, deregulation of NF-B may lead to inflammatory conditions (Yamamoto and Gaynor 2001)

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