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GPX3 is an extracellular glycoprotein that accepts thioredoxin (Trx) and glutaredoxin (Grx) as substrates in addition to GSH [13]

Not only do we need to adopt a personalised approach to patient-centred care, we need to appreciate the need for a holistic approach to medicine

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doi: 10.1111/j.1528-1157.1997.tb01263.x

This review also discusses the regulation of amino acid metabolism in cancer, therapies that are under investigation, and aspects of amino acid metabolism relevant to inhibition with a specific focus on transaminases and amino acid transporters

The July 2026 meeting is intended to gather expert input on whether these nominated substances should be considered for inclusion on the 503A Bulks List