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As was seen in prior studies 6,7,9,16 , while the vast majority of participants receiving semaglutide 2.4 mg had lost weight at the end of the STEP 5 study, a small proportion of participants experienced weight gain

Investigations have centred around its interaction with prostate-related cell models and immune cell pathways

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Laboratory studies have also shown that it can reduce the body's response to acute stress, as it significantly affects the levels of substance P, beta-endorphin and cortisol in the hypothalamus and blood plasma

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