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This can be due to a variety of reasons, including having a diet consisting of high-inflammation foods (red and processed meat, baked goods, deep-fried items, bread, pasta, etc.) versus those that lower inflammation throughout the body (berries, fruits, avocados, nuts, etc.)

Footnotes CONFLICT OF INTEREST The authors declared no competing interests for this work

Hyperinsulinemic euglycemic clamps studies These were performed according to guidelines established by the Mouse Metabolic Phenotyping Center Consortium 168

Minimize ultra-processed foods, excessive added sugars, and alcohol all of which increase oxidative and inflammatory burden on pathways that interact with cognition and Dihexa-related signaling

Verlag Chemie/Academic Press Inc., Weinheim/NewYork

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