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Of late, multiple transcription factors such as TFAP2C, p53, AP-1, STAT, Nrf2, HIF-1, and C/EBP have been linked with the transcriptional regulation of seleno-GPxs [8, 21,22,23,24]

Treatment with RSL3 (a ferroptosis inducer) has been found to downregulate SLC2A3 expression and induce ferroptosis in RA fibroblast-like synoviocytes (RA-FLS) [163]

The synthesis of neurotransmitters by probiotics may influence the physiopathology of AD by modulating the A metabolism, Tau pathology, and inflammation

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The protein p53 encoded by this gene inhibits the development of tumors through the regulation of the cell cycle, apoptosis, genomic stability and other pathways