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Splitface studies involving subcision and other modalities of scar revision on the contralateral side of facial skin were included provided only one treatment modality is used on each side of the skin

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Topical Retinoids Hormonal acne can be well managed with retinoids which are naturally occurring compounds synthesized from vitamin A

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Edge activators cause lipid vesicles bilayer membrane to become less stable, become more deformable, and facilitate vesicles passage through the skins micropores while avoiding the stratum corneum barrier, which is the primary barrier and rate-limiting step for drug diffusion through the skin (163, 164)