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82 Besides, drug-induced ROS can inhibit the PI3K/AKT pathway to suppress cancer cell proliferation by disrupting key pathways critical for tumor growth and survival, as evidenced by studies with (+)-anthrabenzoxocinone in NSCLC and 6-methoxydihydrosanguinarine in breast cancer

J Biol Chem 287:36303641

Prior to the launch of the Juno mission, a NASA space probe launched in 2011, now in orbit around Jupiter, scientists generally thought that other planets would be similar to Earth, where the incoming sunlight generally drives weather and climate

doi: 10.1016/j.pep.2010.12.004

In p21-deficient tumor cells exposed to DNA-damaging agents, apoptosis occurs rapidly, whereas cells with enforced p21 expression survive despite accumulating damage 32

C.ChauffertB.et al
