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NCOA4 expression was found to be reduced in both cell lines upon FAC and erastin treatment
Consequently, this activates the AMPK respiratory complex I, indicating its use in clinical trials and as therapy for OA (167)

Arthritis The hallmarks of osteoarthritis are cartilage destruction and inflammation two conditions that curcumin is able to prevent

Exp Mol Med (2020) 52(9):1496516
doi: 10.1074/jbc.M303477200

Subsequently, ubiquitination-dependent autophagic degradation occurs
