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If SMS-5-generated sphingomyelin was the PGP-14 substrate, we might expect an absence of Nile Red signal within the pharynx epithelium in the sms-5(0) mutant, which is not what we observe

retrospectively analysed the charts of 13 patients (all under the age of 16) who presented with VPAinduced hyperammonemia and encephalopathy between 2012 and 2015

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