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In one 2019 study, both folate and vitamin B12 reduced levels of homocysteine while improving anemia status in a group of participants with relapsing-remitting multiple sclerosis

Despite the positive roles of microglia in response to cuprizone, a complete absence of microglia prevents cuprizone toxicity suggesting that these cells are also pathogenic during cuprizone-induced demyelination [189]

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Endocrinologa y Nutricin (English Edition) 59(8):487490 Reinstatler L et al (2012) Association of biochemical B 12 deficiency with metformin therapy and vitamin B 12 supplements: the National Health and Nutrition Examination Survey, 19992006

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