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"Poor metabolizers," however, appear to totally lack the stereospecific (S)-mephenytoin hydroxylase activity, so both (S)- and (R)-mephenytoin enantiomers are N-demethylated to nirvanol, which accumulates in much higher concentrations

Nature 2014;509:10509

doi: 10.1089/aid.2016.0303

Hautement concentr : 300 mg pour 2 glules

Paths of nutrition in articular cartilage and intervertebral discs
