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6 Conclusions and prospects With ongoing collaboration among the fields of materials science, tissue engineering, and systems immunology, TA-based hydrogels have emerged as promising platforms for next-generation wound management and tissue regeneration

Peptide bond formation joins amino acids through a nucleophilic attack of an -amino group on an activated -carboxyl carbon, releasing water and forming an amide (peptide) bond with partial double-bond character due to resonance delocalization of the nitrogen lone pair into the carbonyl

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Giralt S, Thall PF, Khouri I, Wang X, Braunschweig I, Ippolitti C, Claxton D, Donato M, Bruton J, Cohen A, Davis M, Andersson BS, Anderlini P, Gajewski J, Kornblau S, Andreeff M , Przepiorka D, Ueno NT, Molldrem J, Champlin R

[DOI] [PMC free article] [PubMed] [Google Scholar] Cooper A.J.L., Krasnikov B.F., Niatsetskaya Z.V., Pinto J.T., Callery P.S., Villar M.T., Artigues A., Bruschi S.A