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Those who have had bariatric surgery or other gastrointestinal procedures often have less stomach surface area available for vitamin absorption

Nowadays, desensitisation application is carried out successfully with antibiotics, aspirin, and even many different chemotherapeutic drugs.24 Unfortunately there is no standardised protocol for vitamin B12 desensitisation such as at antibiotics and aspirin

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5,10-Methylene tetrahydrofolate (THF) is required for the synthesis of nucleic acids and is reduced to 5-methyl THF by methylene THF reductase, a flavin-dependent enzyme that uses NADPH as a cofactor