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doi: 10.1016/j.arabjc.2021.103004 90

Growth Hormone Receptor Upregulation The peptide increases the expression of growth hormone receptors on cell surfaces

In chronic stress paradigms, it has been associated with normalized corticotropin-releasing hormone activity and reduced anxiety-like behavior

2018 (3) CD004655

[28] [36] HGF expression is restricted to cells of mesenchymal origin

Likewise, RNA-sequencing analyses in postmortem human studies have yielded evidence of a downregulation of PPP3CA, which encodes for calcium-dependent calmodulin-stimulated protein phosphatase, in patients with CTE compared to healthy subjects, and these patterns were inversely correlated with phosphorylation of tau at Ser202/Thr205 (Seo et al., 2017)