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This review has mapped their pleiotropic actionsranging from redox buffering and immune modulation to epigenetic reprogrammingand highlighted encouraging preclinical synergy with radiotherapy, chemotherapy, and immunotherapy

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These include permeation enhancers, nanoparticle carriers, intestinal patches, and microneedle delivery devices [62]

Acknowledgments We acknowledge the support from the Department of Developmental Cell Biology, Cell Biology Division, Key Laboratory of Cell Biology, Ministry of Public Health, Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University