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Furthermore, none of the treatment groups showed a significant reduction in loss of gastrocnemius muscle mass at study endpoint (16 weeks post SNR)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Russo G, Cioffi G, Di LA, et al

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A randomized, controlled, clinical pilot study assessing the analgesic effect of morphine applied topically onto split-thickness skin wounds