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Brain glutathione concentrations were measured using 7T magnetic resonance spectroscopy, and GSH/GSSG redox ratios were measured from blood samples

Pharmacokinetic/pharmacodynamic (PK/PD) human volunteer studies show dose response across multiple infusion rates (e.g

(Shen et al., 2017) demonstrated that curcumin upregulated hepatic insulin receptor substrate (IRS)-1 and Akt phosphorylation, thereby enhancing insulin sensitivity

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10.1200/JCO.2004.08.048 242 WozniakK

In addition to the MTERF1 gene humans express three additional related genes identified MTERF2, MTERF3, and MTERF4 all of whose encoded proteins localized to the mitochondria