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Both target the same lipolytic region of growth hormone without affecting blood glucose

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[DOI] [PubMed] [Google Scholar] 21.Polley MY, Leung SC, McShane LM, Gao D, Hugh JC, Mastropasqua MG, et al

Combining semaglutide with other glucose-lowering agents (insulin, sulfonylureas) is a documented hypoglycemia risk and belongs strictly under clinical supervision