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In skeletal muscle, hybrid receptors comprise at least half of the insulin receptor (IR) and IGF-IR population 47 , where hybrid receptors preferentially bind IGF-I compared to insulin, and bind IGF-I with equivalent affinity as IGF-IR 48,49

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If you frequently miss doses, discuss timing strategies with your healthcare provider

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Inside the cell: molecular stress response pathways in diabetes pathogenesis

doi: 10.1096/fj.11-190587 12 BaillieG