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Among phytochemicals, flavonoids and polyphenols play pivotal roles in detoxification mechanisms by upregulating antioxidant enzymes, including Glutathione S-Transferase (GST), NAD(P)H Quinone Dehydrogenase 1 (NQO1), and Superoxide Dismutase (SOD), while simultaneously suppressing pro-inflammatory pathways

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In skin biology, theres interest in glutathione because of its proposed roles in: Inhibiting tyrosinase (an enzyme crucial to melanin production) in theory reducing pigment formation

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