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muciniphila-mediated mucus homeostasis reinforces the physical barrier, thereby reducing systemic exposure to intestinal ROS and preventing lipopolysaccharide (LPS) leakage

Recent methodological advancesmulti-omics (transcriptomics, proteomics, metabolomics), high-content phenotypic assays, organotypic 3-D skin models, and standardized in vitro toxicology platformsnow permit rigorous mapping from plant chemistry to cellular responses and safety profiles
Changes in gene expression in rat thymocytes identified by cDNA array support the occurrence of oxidative stress in early magnesium deficiency

Methaemoglobinaemia (methaemoglobin [MetHb] levels in excess of 2%) represents a rare haematological disorder in humans due to the oxidation of haemoglobin (Hb) 10

Despite these limitations, curcumin is increasingly regarded as a promising adjunctive intervention in AD owing to its ability to act through multiple neuroprotective pathways (35)
