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also proved that HIF-1 activation is a pivotal regulator of the IFN--dependent host response that modulates metabolism to eliminate Mtb in in vitro and in vivo settings (241)

Moreover, the studies linking oxidative stress to MS symptoms such as fatigue, depression or cognitive impairment (CI), are scarce

For each of the stimulation intensities, post hoc analysis revealed a significant age-related decrease in fEPSPs only in the xCT +/+ mice (Fig

Through binding to these sequences, m-MITF directly activates the transcription of hundreds of genes in the melanocytic lineage and controls melanocyte proliferation, differentiation, survival, pigment production and various additional processes

Ionizing radiation can cause damage by physically affecting the structural parts of the cell (membrane, cytoskeleton, DNA and RNA structures, proteins), as well as causing oxidative damage by creating many free oxygen radicals at the cell level

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