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Nanoparticles within the range of 50150 nm in size are optimal for avoiding rapid renal clearance and leveraging the enhanced permeability and retention (EPR) effect [96]

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Inhibition of rat prostate carcinogenesis by a 5alpha-reductase inhibitor, FK143

Low-dose naltrexone (LDN), considered in a daily dose of 1 to 5 mg, has been shown to reduce glial inflammatory response by modulating Toll-like receptor 4 signaling in addition to systemically upregulating endogenous opioid signaling by transient opioid-receptor blockade

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