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It also boosts energy, helping to increase activity levels, which is often a concern for many patients

For example, the upregulation of matrix metalloproteinase7 (MMP7) has been leveraged by our group to create an MMP7activatable aPS

STAT3 a key oncogene with dual functions of signal transduction and transcriptional activation, which is hyperactivated in the formation of most human cancers and plays a critical role in cell proliferation, angiogenesis, metastasis, and immunosuppression (El-Tanani et al., 2022)

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When orally administered, NAC undergoes rapid intestinal absorption and is subsequently metabolized by the liver [1]

Thus, while the role of ABC transporters in mediating resistance to chemotherapeutic agents is well established, it is unclear if and how they modulate the response of cancer cells to targeted therapies