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[17] Localized adverse reactions-transient erythema, warmth, pruritus, or mild burning-occur in up to one-third of users and are generally self-limiting

doi: 10.1016/s0022-3476(83)80831-2
Ann Clin Lab Sci 11: 292299

Under the chromatographic conditions of this method, the resolution between crotonoylbetaine and l-carnitine was 1.1 0.9% (Figure 2), the theoretical plates for l-carnitine peak was 2087.0 0.82%, the tailing factor for l-carnitine peak was 1.3 1.54%, and total run time was less than 8 min

2to analyze the relationships between plasma VPA concentrations and VPA-related effects on lactatemia

Although this can happen anywhere on your skin, its most common on your face
