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Description
The thumbs functional units are the proximal and distal phalanges, interphalangeal, metacarpal, and carpometacarpal joints

However, due to the lack of specificity and the strong diuretic side effects, the GST-targeted clinical usage of EA and its GSH conjugate is limited [154,157]

The Lancet 383 , 22532264 (2014)

Key Takeaway: GHK-Cu is water-soluble, generally stable in neutral aqueous buffers, and stored long-term as a lyophilized powder at 20 C

Another study also reported that activation of Nrf2/HO-1 attenuated neuronal injury and depressive-like behaviors, although the BDNF-extracellular regulated protein kinases (ERK)1/2-cAMP-response element binding protein (CREB) axis also contributed to these neuroprotective effects (Zhang J

November 2011
