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421,459,460 The thalamus plays a pivotal role in modulating and processing somatosensory inputs before they reach the cerebral cortex and may serve as a central biomarker for neuropathic pain in diabetes mellitus

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Although certain integrin subtypes (e.g., 1-integrin) may exert context-dependent tumor-suppressive effects via p21/p27-mediated growth arrest, the prevailing outcome in fibrotic livers is a tumor-permissive microenvironment (153)

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