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Increased in synaptic density and improvement in executive functions was also observed in healthy aged mice after treatment with CA 53

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NAD- Nicontinamide Adenine Dinucleotide is a coenzyme central to metabolism

doi:10.1073/pnas.0813409106, PMID: 19223582 Vali S, Mythri RB, Jagatha B, Padiadpu J, Ramanujan KS, Andersen JK, Gorin F, Bharath MM (2007) Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinsons disease: a dynamic model