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is referred to as the respiratory burst. [Note: Active NADPH oxidase is a membrane-associated complex containing a flavocytochrome plus additional peptides that translocate from the cytoplasm upon activation of the leukocyte

The name reflects its original observed effect: it promoted delta wave brain activity, the slow waves that dominate the deepest stages of sleep

2025;31:e70016

Monitoring typically includes clinical response assessment and follow-up blood tests

Front Physiol 8:43

However, as mentioned before, several other studies show that not age per se but rather age-related renal insufficiency may increase serum levels of HCys and particularly MMA since GFR declines with age [83]