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Moreover, the ability of -tocopherol to act as a pro-oxidant (reducing agent) or antioxidant depends on whether all of the -tocopherol becomes consumed in the conversion from ferric to ferrous iron or whether, following this interaction, residual -tocopherol is available to scavenge the resultant ROS (Yamamoto & Nike, 1988)

Randomised double-blind placebo-controlled study of interferon -1a in relapsing/remitting multiple sclerosis

Eur J Pharmacol 1999;379:1931

[DOI] [PubMed] [Google Scholar] 15.Zhang J., He X.C., Tong W.G., Johnson T., Wiedemann L.M., Mishina Y., Feng J.Q., Li L

In addition, riboflavin and pyridoxine, which requires riboflavin for its activation, have been shown to have intrinsic neuroprotective properties against glutamate excitotoxicity