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The injections typically use a form of vitamin B12 known as cyanocobalamin or hydroxocobalamin

On average one in ten people are believed to be deficient in Vitamin B12, that is an astonishing six million suffering from the consequences of having less than the optimum amount of B12 in their system

People with kidney disease should avoid high doses of B vitamins.

Thyroid function and nutritional markers TSH (thyroid stimulating hormone) monitoring is recommended for people on semaglutide, primarily because GLP-1 receptor agonists as a drug class have been associated with C-cell hyperplasia in animal studies, which raised theoretical concerns about thyroid cancer risk

Pairing semaglutide with vitamin B12 is done to help reduce appetite while also supporting energy and metabolism