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The first AChE structure to be described was from the Pacific electric ray Torpedo californica , featuring 14 -helices surrounding a 12-stranded mixed -sheet with an active site comprising a planar array formed by three residues in loops within highly conserved regions (Sussman et al., 1991
It plays a key role in detoxification, helping to eliminate harmful toxins and pollutants from the body
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Drug discovery targeting nicotinamide phosphoribosyltransferase (NAMPT): updated progress and perspectives
