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Butyrate suppresses demyelination and enhances remyelination

Given the challenges posed by chronically neurotoxic host environments, current transplantation strategies are increasingly focused on combining neuronal replacement with the localized or systemic delivery of anti-inflammatory or neuroprotective agents

Blood Cells Mol Dis

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In general, mB12/LDFA treatment had a significant effect on glutathione and cysteine metabolism with a medium effect size while BH4 had a significant effect on methylation and markers of chronic oxidative stress with a large effect size