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Methotrexate chemotherapy induces persistent tri-glial dysregulation that underlies chemotherapy-related cognitive impairment

Two independent researchers (AM and SD) screened the titles and abstracts of all retrieved articles, with a particular emphasis on those published in journals ranked within the first quartile (Q1) of their respective subject categories
PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia

Interestingly, in Arabidopsis suspension cells transcriptional up-regulation of GCL in response to various oxidative stresses was not observed, even though both GCL activity and cellular glutathione levels increased (May et al., Localization of Glutathione Synthesis in Plants The localization of GCL and GS plays a major role in the biosynthesis of glutathione

Endoperoxides was separated on a Luna C18 reverse phase column, 250 4.6 mm, 5 M particle size (Phenomenex, Torance, CA) and monitored at 210 nm

Headaches: Occasionally reported, particularly during initial use
