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Consequently, further systematic studies are required to elucidate the synergistic mechanism and the optimal combination of CB-839 with other drugs or therapeutics

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The designation of SCHAD for the enzyme encoded by the HSD17B10 can lead to confusion since the enzyme encoded by the HADH (hydroxyacyl-CoA dehydrogenase) gene, which is involved in medium- and short-chain fatty acid oxidation, is also identified as short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD)

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Cysteine-SOH interacts with another cysteine, producing H 2 O and a disulfide bond