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doi: 10.1371/journal.pone.0137680

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This guide covers the biochemistry, clinical evidence, therapeutic uses, and the key differences between oral supplementation and IV delivery

Teichret J, Hermann R, Ruus P, Preiss R (2003) Plasma kinetics, metabolism, and urinary excretion of alpha-lipoic acid following oral administration in healthy volunteers
Thus, maternal separation can lead to the offspring having lower voluntary food intake and a preference for foods low in carbohydrates (Penke et al., 2001), while social isolation in previously maternally separated rats elevates food intake and weight gain (Ryu et al., 2009)
Vitamin B12 deficiency in elderly patients
