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By blocking the leptin signaling pathway, it is possible to efficiently restore the number and function of Treg cells, which would slow the progression of the disease (234)

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Mitochondrial Vulnerability: Mitochondria cannot synthesise glutathione and depend entirely on membrane transporters for supply

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Under the mediation of p38MAP kinase, heat shock factor 1 (HSF1)-dependent activation of PROM2 transcription can be inhibited by the application of HSF1 inhibitors