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They require a specialized, active transport mechanism, scientifically referred to as the "carnitine shuttle," to gain entry into the mitochondrial matrix where they can be burned for fuel

In a Phase III trial, abiraterone conferred a nearly 4-month survival advantage to patients with metastatic CRPC refractory to docetaxel

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doi: 10.1016/S1473-3099(05)70216-4

PMC 4163187

Moreover, data on molecular diagnostics on CRP are discussed, and possible etiologies of false test results are highlighted
