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In the Mediterranean populations the enzymatic deficiency is much more severe and frequent than in the population of North American black race 32 , where the defect was identified in the red blood cells

Arabidopsis AtFer1, one of the best characterized plant ferritin isoforms to date, strongly accumulates upon treatment with excess iron, via an NO-mediated pathway

discovered that comutations in STK11 and KEAP1 suppress SCD1 expression, thereby promoting MUFA synthesis and reducing PUFA levels, which ultimately suppresses ferroptosis in lung cancer cells [78]

The chelation of metallothionein with metal ions is one of the most crucial pathways for metal detoxification in living cells [23]

Molecular mechanisms: connections between nonalcoholic fatty liver disease, steatohepatitis and hepatocellular carcinoma

Nov 2014;16(11):699-705