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Moreover, in IGF-1R null tumors, IGF-2 increases -catenin levels, a key mediator of EMT

[DOI] [PubMed] [Google Scholar] Casas AI, Dao VT, Daiber A, Maghzal GJ, Di Lisa F, Kaludercic N, Leach S, Cuadrado A, Jaquet V, Seredenina T, Krause KH, Lpez MG, Stocker R, Ghezzi P, Schmidt HH

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The suitability of each compound for ISF versus blood-based sensing is thus determined largely by its molecular size, hydrophobicity, and binding characteristics
