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Additional regulators include aryl hydrocarbon receptor nuclear translocator in acute myeloid leukemia (AML), CREB-1, activating transcription factor 1 (ATF-1), and HIF-1 [162,163]

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Also, the membrane fluidity of cancer cells is more than healthy ones, which makes them more susceptible to ACPs that can destabilize the membrane leading to death

27 , 30 Additionally, the Sonic Hedgehog (SHH) pathway, when aberrantly activated, suppresses autophagy through the AKT-mTOR axis, increasing the number of myofibroblasts and enhancing the expression of fibrotic markers

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